PR Newswire
02 Aug 2022, 11:07 GMT+10
DAEJEON, South Korea, Aug. 2, 2022 /PRNewswire/ -- GenKOre, a biotech start-up in Korea, succeeded in the development of ABEs based on its own hypercompact gene-editing technology and had the relevant study published on Nature Chemical Biology on August 2, 2022.
GenKOre (homepage: www.genkore.com) is a business spun off from the Korea Research Institute of Bioscience and Biotechnology (KRIBB), which is a government-invested research institute in Korea. It has platform business through proprietary gene-editing platform. GenKOre succeeded in the development of a hypercompact CRISPR system with AAV delivery compatibility termed TaRGET (Tiny nuclease/augment RNA-based Genome Editing Technology), which was published on Nature Biotechnology in 2021. The AAV-loadable ABE technology was derived from the TaRGET platform.
The hypercompact ABEs developed by GenKOre is characterized by compactness in size that can be delivered using AAV and boast of specific and versatile base-editing activity, which was also validated in vivo. Previous base-editing technology was developed based on such a 'big' SpCas9 nuclease that it cannot be delivered by payload-limiting AAV vectors and has been thus confined for hepatic delivery. This new base-editing technology is expected to provide various in vivo treatment options for genetic diseases through AAV delivery.
GenKOre recently expanded its research facility in Seoul in an effort to attract a large number of human resources for the development of hypercompact ABEs-based gene therapy, seeking collaborations with pharmaceutical companies and academia. Besides, it is expanding business to ex vivo gene therapy by making strategic alliance with companies with expertise in immune cells and hematopoietic stem cells. The ABE platform will be thus employed to develop ex vivo gene-editing therapy.
Details of said content published on Nature Chemical Biology can be checked at: https://www.nature.com/articles/s41589-022-01077-5.
GenKOre website: www.genkore.com
SOURCE GenKOre
Get a daily dose of Vietnam Tribune news through our daily email, its complimentary and keeps you fully up to date with world and business news as well.
Publish news of your business, community or sports group, personnel appointments, major event and more by submitting a news release to Vietnam Tribune.
More InformationWASHINGTON D.C.: The U.S. will participate in a joint military exercise in mid-October with India, less than 62 miles from ...
YANGON, Myanmar - Honeys Holdings, a Japanese clothing retailer that manufactures much of its product line in Myanmar, has decided ...
KATHMANDU, Nepal - In Nepal, the existence of another lizard species has been verified. The additional lizard species was discovered ...
DELHI, India: India's defense ministry has said that the country has offered to sell 18 Tejas light single-engine jet combat ...
KUALA LUMPUR, Malaysia - After almost four years, the Bangladesh High Commission in Malaysia on Tuesday welcomed the first group ...
BIRMINGHAM, UK - Arshad Nadeem was hailed by the entire country late Sunday for his outstanding performance in the Commonwealth ...
WASHINGTON D.C.: The U.S. will participate in a joint military exercise in mid-October with India, less than 62 miles from ...
SEOUL, South Korea: South Korea has launched a domestically manufactured lunar orbiter that took off from Florida's Cape Canaveral Space ...
MOSCOW, Russia: A leading Russian scientist in the field of hypersonic flight, Dr. Alexander Shiplyuk, has been arrested on suspicion ...
LOS ANGELES, California: During a meeting that was disrupted by protesters this week, the Los Angeles City Council voted to ...
WASHINGTON D.C.: The U.S. Justice Department announced this week that former Puerto Rico governor Wanda Vazquez has been arrested in ...
OTTAWA, Ontario: Military trainers from Canada will head to the United Kingdom to teach Ukrainians new techniques for fighting the ...